Secondary prophylaxis with anti-inhibitor coagulant complex (AICC) : from anecdote to reality.

Anti-inhibitor Coagulant Complex (Autoplex) for treatment of factor VIII inhibitors in hemophilia.

Fourteen individuals with severe hemophilia complicated by factor VIII inhibitors (1 to 132 Bethesda Units) were treated for 33 bleeding episodes with a new activated prothrombin complex concentrate, Anti-Inhibitor Coagulant Complex (Autoplex, Hyland, Glendale, Calif.). Excellent or good results were observed in 21 of 25 minor bleeding episodes treated, which included joint, soft tissue, and mu...

Moving from anecdote to evidence.

Anti-inflammatory, anti-coagulant, anti-biotic?

2013; 109: 684-695. Systemic activation of inflammatory cascades and coagulation are a hallmark in the pathogenicity of infectious diseases that significantly contribute to morbidity and mortality of severely infected patients. Complications are often evoked by an overreaction of host defense systems to the infection and thus many antimicrobial drugs have been developed that have anti-inflammat...

Israeli-Arab Relations; from Dream to Reality

Abstract:This study intends to review Israel's efforts to increase political and economic relations with Arab countries. It is clear that most Arab countries did not have any ties with Israel since the 1980s, and only two Egyptian states had established political relations with Israel since the 1973 war. But over the past few years, and especially after the start of the third millennium, ...

Cognition and cannabis: from anecdote to advanced technology.

Whether the use of cannabis causes lasting cognitive or behavioural alteration has been controversial for decades. Studies addressing the problem have often been confounded by failure to account for residual acute effects or withdrawal and by failure to measure cognitive function before drug use. Investigative strategies have included neuropsychological testing, brain activation during cognitiv...